Late Side Effects of Radiotherapy
Nejma N. Mubarak1, Hussain S. Akbar2
1 Kirkuk Technical Institute / Community Health Dept.
2 Kirkuk University / College of Science - Physics Dept.
The study carried on 40 women with breast cancer treated by radiotherapy at Atomic medical
center(Bagdad/Iraq) and Gülhane hospital (Ankara –Turkey) during 2007 . The data was
collected by direct interview with the patients whose age range was (48-75) years . The research
done after ( 2-11) years of treatment. Mild to severe type of mouth dryness was noticed in
almost all the cases with variety of teeth and gum problems.80% of the patients developed diabetes
mellitus, 30% of them were with no family history of disease.Edema of the arm (lymphoedema) in
the same side of the affected breast occurred in 25% of the patients. Cardiac manifestations
recorded in 15% including dyspnea due to congestion and pericardial effusion (diagnosed by
Echocadiography) , cardiacmyopathy due to radiotherapy may cause such manifestations .
Fibrosis of the lung causing shortness of breath on exertion and liability to chest infection and
allergy diagnosed by chest tomography in 10% of the patients. 10% of the patients developed cataract
in one eye (in the same side of the tumor).The ionizing radiation which is used in treatment of
malignancy may cause cell damage in healthy tissues exposed to it because of its high energy
capable to remove electron from the atoms in the biological molecules of the cells leading to their
damage and appearance of some clinical problems in the treated patients.Modern sophisticated
methods are designed such as radio-immunotherapy, conformal radiotherapy that match the
case precisely, using radio-sensitizer drugs and accurate dosing in order to reduce the unwanted
clinical effects of radiotherapy and the doctors have to balance the likelihood of cure with the risk
of side effects.
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Keywords: Cancer, Radiotherapy, lung fibrosis, cardiomyopathy.
kirkuk university journal scientific studies
Publisher: Kirkuk University
Language: Arabic and English
This journal is Open Access